A rare disease that occurs when a protein called amyloid builds up in organs. This buildup can make the organs not work properly.
Not having enough healthy red blood cells or hemoglobin to carry oxygen to the body's tissues. Having anemia can cause tiredness, weakness and shortness of breath.
Occurs when the immune system mistakenly creates antibodies that attack tissues in the body. These antibodies can cause blood clots to form in arteries and veins.
Autoimmune Hemolytic Anemias
A rare immune disorder that happens when your body produces antibodies that destroy red blood cells.
An illness that can lead to bruising and bleeding. Low levels of the cells that help blood clot (platelets), most often cause the bleeding.
Benign Hematologic Conditions
Blood conditions that prevent blood cells and platelets from carrying out their intended job.
When blood lacks certain clotting factors. Most bleeding disorders are inherited, but in rare cases they can be developed later in life if the body forms antibodies that fight against the blood's natural clotting factors.
Chronic Lymphocytic Leukemia
Type of cancer of the blood and bone marrow.
Chronic Myelogenous Leukemia
An uncommon type of cancer of the bone marrow.
Chronic Myelomonocytic Leukemia
A type of chronic blood cancer in which a person's bone marrow does not make blood effectively.
Cutaneous T-cell Lymphoma
A rare type of cancer that begins in the white blood cells called T-cells (T lymphocytes). These cells normally help your body's germ-fighting immune system, but in the case of this disease, they develop abnormalities that make them attack the skin.
A blood disorder that causes a high number of blood cells called platelets to form.
A genetic bone marrow disease inherited via both parents (parents are carriers and don't necessarily have the condition).
Hairy Cell Leukemia
Cancer of the white blood cells, in which the body makes too many that are unhealthy and undergo changes to become leukemia cells.
A group of disorders passed down through families in which there is abnormal production or structure of the hemoglobin molecule.
Where the blood doesn't clot in the typical way because it doesn't have enough blood-clotting proteins.
Heriditary Hemolytic Anemias
Caused by a defect in the red blood cells themselves, resulting when one or more genes that control red blood cell production don't function properly.
Hodgkin's Lymphoma (Hodgkin's Disease)
Cancer that affects the lymphatic system, which is part of the body's germ-fighting immune system. In Hodgkin's lymphoma, white blood cells, called lymphocytes, grow out of control, causing swollen lymph nodes and growths throughout the body.
A group of blood disorders that occur when you have high numbers of eosinophils — white blood cells that play an important role in the immune system.
Immune Thrombocytopenia (ITP)
An illness that can lead to bruising and bleeding. Low levels of the cells that help blood clot, also known as platelets, most often cause the bleeding.
Iron Deficiency Anemia
Without enough iron, the body can't produce enough hemoglobin in red blood cells that enables them to carry oxygen . As a result, iron deficiency anemia may leave you tired and short of breath.
Large Granular Lymphocyte Disorders
Characterized by enlarged lymphocytes, containing noticeable granules, which can be seen when the blood is examined under a microscope.
A type of cancer of the body's blood-forming tissues, including the bone marrow and the lymphatic system.
Cancer of the lymphatic system, which is part of the body's germ-fighting network. The lymphatic system includes the lymph nodes and glands, spleen, thymus gland and bone marrow.
Monoclonal Gammopathy of Undetermined Significance (MGUS)
A condition in which an atypical protein is found in the blood. MGUS usually causes no problems, but can lead to serious diseases, including some forms of blood cancer.
A cancer that forms in a type of white blood cell called a plasma cell. Healthy plasma cells help fight infections by making proteins called antibodies which find and attack germs.
A group of disorders caused by blood cells that are poorly formed or don't work properly.
An uncommon type of bone marrow cancer that disrupts your body's normal production of blood cells.
Natural Killer Cell Leukemia
Part of the Large Cell Granular Lymphocyte disorders; characterized by aggressive and nonaggressive versions.
Cancer that begins in the lymphatic system where white blood cells called lymphocytes grow abnormally and can form growths (tumors) throughout the body.
Characterized by bone lesions that are much harder and denser than regular bone.
Paroxysmal Nocturnal Hemoglobinuria
A disorder where part of the immune system attacks and damages red blood cells and platelets.
A condition in which there are too few platelets, the blood cells that prevent bleeding.
A blood disorder that damages the nerves and affects other parts of the body. POEMS stands for these signs and symptoms:
- Polyneuropathy - Numbness, tingling and weakness in the legs and difficulty breathing
- Organomegaly - enlarged spleen, liver or lymph nodes
- Endocrinopathy/edema - Abnormal hormone levels
- Monoclonal-protein - Abnormal bone marrow cells (plasma cells) that produce a protein that can be found in the bloodstream.
- Skin Changes - more color than normal on the skin; red spots, possibly thicker skin and increase facial or leg hair.
A type of blood cancer that causes bone marrow to make too many red blood cells.
Sickle Cell Anemia
An inherited disorder that affects the shape of red blood cells and can result in slower or blocked blood flow.
An inherited blood disorder that causes the body to have less hemoglobin than normal.
Thrombocytopenia (low platelet count)
A condition characterized by a low blood platelet count.
Where the body produces too many platelets.
Vitamin Deficiency Anemia
Lack of healthy red blood cells, caused by lower than usual amounts of vitamin B-12 and folate.
Von Willebrand Disease
A lifelong bleeding disorder in which the blood doesn't clot properly.
A type of Non-Hodgkin's Lymphoma in which the bone marrow produces too many abnormal white blood cells that crowd out healthy blood cells.